This work presents a 3D finite element analysis of the adult human mandible presenting dental misalignment, carried out using FEM. The study aims to evaluate the mechanical response of the mandible and teeth during a numerically simulated alignment process by means of imposed displacements, following established finite element methodologies widely used in biomechanical analysis [1,3]. A complete 3D scan of the lower jaw was used to generate an initial STL geometric model. This model was subsequently processed in ANSYS SpaceClaim to remove geometric defects and adapt it for numerical simulation. The resulting geometry was imported into ANSYS Mechanical, where the material properties of the mandibular bone and the different dental components were defined in accordance with values commonly adopted in dental biomechanics studies [3]. The geometric model was discretized using a Body-Fitted Cartesian (BFC) meshing algorithm, resulting in a large-scale numerical model comprising more than 2.5 million nodes and approximately 570,000 finite elements. Appropriate boundary conditions were imposed at the mandibular extremities, and prescribed displacements were applied to nodes located on selected teeth to simulate the alignment process, as performed in previous orthodontic finite element investigations [2,4]. The analysis was performed through multiple load steps, allowing the evaluation of the reaction forces required for dental alignment, the resulting displacements, and the stress distribution in both the teeth and the mandibular bone. The obtained results provide insight into the mechanical behaviour of the mandible during orthodontic alignment and enable the identification of critical stress regions. The most relevant conclusions of the study are discussed, demonstrating the potential of finite element modeling as a tool to support orthodontic and biomechanical analyses, in agreement with prior mandibular and orthodontic simulation studies [2,6].